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Aspartic Acid Racemization and Collagen Degradation Markers Reveal an Accumulation of Damage in Tendon Collagen That Is Enhanced with Aging

Little is known about the rate at which protein turnover occurs in living tendon and whether the rate differs between tendons with different physiological roles. In this study, we have quantified the racemization of aspartic acid to calculate the age of the collagenous and non-collagenous components...

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Detalhes bibliográficos
Main Authors: Thorpe, Chavaunne T., Streeter, Ian, Pinchbeck, Gina L., Goodship, Allen E., Clegg, Peter D., Birch, Helen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871433/
https://ncbi.nlm.nih.gov/pubmed/20308077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077503
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