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A Novel Approach for Untargeted Post-translational Modification Identification Using Integer Linear Optimization and Tandem Mass Spectrometry

A novel algorithm, PILOT_PTM, has been developed for the untargeted identification of post-translational modifications (PTMs) on a template sequence. The algorithm consists of an analysis of an MS/MS spectrum via an integer linear optimization model to output a rank-ordered list of PTMs that best ma...

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Detalhes bibliográficos
Main Authors: Baliban, Richard C., DiMaggio, Peter A., Plazas-Mayorca, Mariana D., Young, Nicolas L., Garcia, Benjamin A., Floudas, Christodoulos A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871412/
https://ncbi.nlm.nih.gov/pubmed/20103568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900487-MCP200
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