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Atriopeptin inhibition of thrombin-mediated changes in the morphology and permeability of endothelial monolayers.

To determine the role of endothelial atriopeptin (AP) receptors, we examined the effect of AP-III on the morphology and macromolecular permeability of monolayer cultures of bovine aortic endothelial cells. AP-III alone (10(-9)-10(-6) M) had no observable effect on the morphology of the monolayers or...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Baron, D A, Lofton, C E, Newman, W H, Currie, M G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287139/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2524068/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.9.3394
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