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Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector.

The role of the X region of the genome of the human T-cell leukemia virus type I (HTLV-I) in the immortalization of lymphocytes has been difficult to distinguish from its role in viral replication as this region encodes at least two genes, tax and rex, required for replication and the expression of...

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Detalhes bibliográficos
Main Authors: Grassmann, R, Dengler, C, Müller-Fleckenstein, I, Fleckenstein, B, McGuire, K, Dokhelar, M C, Sodroski, J G, Haseltine, W A
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC287130/
https://ncbi.nlm.nih.gov/pubmed/2541443
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