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Developmental control of lymphokine gene expression in fetal thymocytes during T-cell ontogeny.

We have used the technique of in situ hybridization to investigate the expression of lymphokine genes by immature thymocytes during intrathymic development. In 13-day fetal thymocytes a population of cells constitutively produces low levels of interleukin 2 (IL-2) and interleukin 4 (IL-4) mRNAs. A s...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Carding, S R, Jenkinson, E J, Kingston, R, Hayday, A C, Bottomly, K, Owen, J J
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2497464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.9.3342
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