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MMP-9/TIMP-1 Imbalance Induced in Human Dendritic Cells by Porphyromonas gingivalis

Matrix metalloproteinase-9 (MMP-9) cleaves collagen, allowing leukocytes to traffic towards the vasculature and the lymphatics. When MMP-9 is unregulated by tissue inhibitor of metalloproteinase 1 (TIMP-1), this can lead to tissue destruction. Dendritic cells (DCs) infiltrate the oral mucosa increas...

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Bibliographic Details
Main Authors: Jotwani, Ravi, Eswaran, S.V.K., Moonga, Surinder, Cutler, Christopher W.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871062/
https://ncbi.nlm.nih.gov/pubmed/20030715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-695X.2009.00637.x
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