Dominant Mutations in the Late 40S Biogenesis Factor Ltv1 Affect Cytoplasmic Maturation of the Small Ribosomal Subunit in Saccharomyces cerevisiae

In eukaryotes, 40S and 60S ribosomal subunits are assembled in the nucleus from rRNAs and ribosomal proteins, exported as premature complexes, and processed in final maturation steps in the cytoplasm. Ltv1 is a conserved 40S ribosome biogenesis factor that interacts with pre-40S complexes in vivo an...

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Bibliographic Details
Main Authors: Fassio, Claire A., Schofield, Brett J., Seiser, Robert M., Johnson, Arlen W., Lycan, Deborah E.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2010
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870955/
https://ncbi.nlm.nih.gov/pubmed/20215468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.115584
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