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Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

Hepatocytes are well coupled by gap junctions, which allow the diffusion of small molecules between cells. Although gap junctions in many tissues are permeable to molecules larger than cAMP and in several preparations gap junctions pass cAMP itself, little direct evidence supports permeation by othe...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sáez, J C, Connor, J A, Spray, D C, Bennett, M V
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2784857/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2708
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