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Monte Carlo simulation of equilibrium globular protein folding: alpha-helical bundles with long loops.

To help elucidate the general rules of globular protein folding, computer simulations of the conformational transition in model proteins having the left-handed, four-helix bundle motif in which the helices are joined by one or two long loops, as in apoferritin and somatotropin, respectively, have be...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Sikorski, A, Skolnick, J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2704742/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2668
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