A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs.

Amphibian eggs and embryos as well as mammalian cells have been reported to contain an activity that unwinds double-stranded RNA. We have now found that adenosine residues have been modified in the RNA products of this unwinding activity. Although the modified RNA remains double-stranded, the modifi...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wagner, R W, Smith, J E, Cooperman, B S, Nishikura, K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286974/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2704740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2647
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