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Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.

We present a cascade of proteolytic events catalyzed by the proteases secreted by cultured keratinocytes and fibroblasts that results in the activation of interstitial procollagenase. Cultured human skin fibroblasts constitutively secrete interstitial collagenase and stromelysin as proenzymes. In co...

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Autors principals: HE, C S, Wilhelm, S M, Pentland, A P, Marmer, B L, Grant, G A, Eisen, A Z, Goldberg, G I
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC286971/
https://ncbi.nlm.nih.gov/pubmed/2468156
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