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Native and mutant 5-lipoxygenase expression in a baculovirus/insect cell system.

Human 5-lipoxygenase (EC 1.13.11.34), the key enzyme involved in the transformation of arachidonic acid to the potent biologically active leukotrienes, has been overexpressed in insect cells using a baculovirus expression system. A recombinant baculovirus (3B6) carrying the human 5-lipoxygenase codi...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Funk, C D, Gunne, H, Steiner, H, Izumi, T, Samuelsson, B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2649885/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2592
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