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Why Aire? Compensating for late bloomers
The question under analysis in this commentary is, what was the evolutionary selection pressure that necessitated the ectopic expression of a subset of peripheral self-antigens in the thymus and by peripheral APC? The suggestion is that antigen expression is delayed until after the immune system is...
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| Huvudupphovsman: | |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869625/ https://ncbi.nlm.nih.gov/pubmed/19688745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939628 |
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