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A Forward Genetic Screen in Mice Identifies Sema3A(K108N), which Binds to Neuropilin-1 but Cannot Signal
We have performed a three-generation, forward genetic screen to identify recessive mutations that affect the patterning of the peripheral nervous system. Using this assay, we identified Sema3A(K108N), a novel loss-of-function allele of Sema3A. Class 3 semaphorins, which include Sema3A, are structura...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for Neuroscience
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869466/ https://ncbi.nlm.nih.gov/pubmed/20410128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5061-09.2010 |
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