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A Domesticated piggyBac Transposase Plays Key Roles in Heterochromatin Dynamics and DNA Cleavage during Programmed DNA Deletion in Tetrahymena thermophila

Transposons comprise large fractions of eukaryotic genomes and provide genetic reservoirs for the evolution of new cellular functions. We identified TPB2, a homolog of the piggyBac transposase gene that is required for programmed DNA deletion in Tetrahymena. TPB2 was expressed exclusively during the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cheng, Chao-Yin, Vogt, Alexander, Mochizuki, Kazufumi, Yao, Meng-Chao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869380/
https://ncbi.nlm.nih.gov/pubmed/20357003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-12-1079
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