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The Set3/Hos2 Histone Deacetylase Complex Attenuates cAMP/PKA Signaling to Regulate Morphogenesis and Virulence of Candida albicans

Candida albicans, like other pleiomorphic fungal pathogens, is able to undergo a reversible transition between single yeast-like cells and multicellular filaments. This morphogenetic process has long been considered as a key fungal virulence factor. Here, we identify the evolutionarily conserved Set...

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Autori principali: Hnisz, Denes, Majer, Olivia, Frohner, Ingrid E., Komnenovic, Vukoslav, Kuchler, Karl
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869326/
https://ncbi.nlm.nih.gov/pubmed/20485517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000889
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