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Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro.

Subtelomeric deletions are responsible for the loss of expression of several Plasmodium falciparum antigens, including the knob-associated histidine-rich protein (KAHRP). Such deletions are detectable by two-dimensional pulsed-field gradient electrophoresis (PFGE) in which the chromosomes separated...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Biggs, B A, Kemp, D J, Brown, G V
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286926/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2648403/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.7.2428
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