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Phospholipase D2 Mediates Acute Aldosterone Secretion in Response to Angiotensin II in Adrenal Glomerulosa Cells

In primary bovine adrenal glomerulosa cells, the signaling enzyme phospholipase D (PLD) is suggested to mediate priming, the enhancement of aldosterone secretion after pretreatment with and removal of angiotensin II (AngII), via the formation of persistently elevated diacylglycerol (DAG). To further...

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Autors principals: Qin, Haixia, Frohman, Michael A., Bollag, Wendy B.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869249/
https://ncbi.nlm.nih.gov/pubmed/20219982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1159
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