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Thromboxane Receptor Activates the AMP-Activated Protein Kinase in Vascular Smooth Muscle Cells via Hydrogen Peroxide

Thromboxane A(2) receptor (TPr) stimulation induces cellular hypertrophy in vascular smooth muscle cells (VSMCs); however, regulation of VSMC hypertrophy remains poorly understood. Here we show that TPr stimulation activates AMP-activated kinase (AMPK), which in turn limits TPr-induced protein synth...

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Bibliografiske detaljer
Main Authors: Zhang, Miao, Dong, Yunzhou, Xu, Jian, Xie, Zhonglin, Wu, Yong, Song, Ping, Guzman, Melissa, Wu, Jiliang, Zou, Ming-Hui
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869198/
https://ncbi.nlm.nih.gov/pubmed/18063812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.163253
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