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Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma.

Platelet-activating factor (PAF) has been implicated as a mediator of inflammation, allergy, shock, and thrombosis. A specific degradative enzyme, PAF acetylhydrolase (EC 3.1.1.47), is found in plasma and could regulate the concentration of PAF in blood. In plasma, 70% of the PAF acetylhydrolase is...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Stafforini, D M, Carter, M E, Zimmerman, G A, McIntyre, T M, Prescott, S M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2928339/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.7.2393
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