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Cloning of Separate Meilingmycin Biosynthesis Gene Clusters by Use of Acyltransferase-Ketoreductase Didomain PCR Amplification

Five meilingmycins, A to E, with A as the major component, were isolated from Streptomyces nanchangensis NS3226. Through nuclear magnetic resonance (NMR) characterization, meilingmycins A to E proved to be identical to reported milbemycins α11, α13, α14, β1, and β9, respectively. Sequencing of a pre...

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Main Authors: He, Yunlong, Sun, Yuhui, Liu, Tiangang, Zhou, Xiufen, Bai, Linquan, Deng, Zixin
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869129/
https://ncbi.nlm.nih.gov/pubmed/20348291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02262-09
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