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Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress and cell death in nephropathy

Cisplatin is an important chemotherapeutic agent available; however the nephrotoxicity is limiting its clinical use. Enhanced inflammatory response and oxidative/nitrosative stress appear to play a key role in the development of cisplatin-induced nephropathy. Activation of cannabinoid-2 (CB(2)) rece...

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Autors principals: Mukhopadhyay, Partha, Rajesh, Mohanraj, Pan, Hao, Patel, Vivek, Mukhopadhyay, Bani, Bátkai, Sándor, Gao, Bin, Haskó, György, Pacher, Pál
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869084/
https://ncbi.nlm.nih.gov/pubmed/19969072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.11.022
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