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The Impact of Gene-Environment Dependence and Misclassification in Genetic Association Studies Incorporating Gene-Environment Interactions

The possibility of gene-environment interaction can be exploited to identify genetic variants associated with disease using a joint test of genetic main effect and gene-environment interaction. We consider how exposure misclassification and dependence between the true exposure E and the tested genet...

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Detalhes bibliográficos
Main Authors: Lindström, Sara, Yen, Yu-Chun, Spiegelman, Donna, Kraft, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869071/
https://ncbi.nlm.nih.gov/pubmed/19521099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000224637
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