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Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

Binding of peptide hormones to surface membrane receptors leads to the transcription of specific genes within relevant target cells. How these signals are transduced to alter gene expression is largely unknown, but this mechanism probably involves a sequence of enzymatic steps that activate factors...

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Détails bibliographiques
Auteurs principaux: Osborn, L, Kunkel, S, Nabel, G J
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC286907/
https://ncbi.nlm.nih.gov/pubmed/2494664
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