Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes.

We have investigated the biochemical basis for the activation of interleukin 2 receptor alpha-subunit (IL-2R alpha) gene expression in primary human T lymphocytes by a cytokine (tumor necrosis factor alpha), a T-cell mitogen (phorbol 12-myristate 13-acetate), and the transactivator protein (Tax) fro...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Lowenthal, J W, Ballard, D W, Böhnlein, E, Greene, W C
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1989
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286906/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2494663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.7.2331
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