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Optimal DNA Pooling-Based Two-Stage Designs in Case-Control Association Studies
Study cost remains the major limiting factor for genome-wide association studies due to the necessity of genotyping a large number of SNPs for a large number of subjects. Both DNA pooling strategies and two-stage designs have been proposed to reduce genotyping costs. In this study, we propose a cost...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
S. Karger AG
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868915/ https://ncbi.nlm.nih.gov/pubmed/18931509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000164398 |
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