The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs

BACKGROUND: Infected humans make protective antibody responses to the PfEMP1 adhesion antigens exported by Plasmodium falciparum parasites to the erythrocyte membrane, but little is known about the kinetics of this antibody-receptor binding reaction or how the topology of PfEMP1 on the parasitized e...

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Main Authors: Joergensen, Lars M, Salanti, Ali, Dobrilovic, Tina, Barfod, Lea, Hassenkam, Tue, Theander, Thor G, Hviid, Lars, Arnot, David E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868858/
https://ncbi.nlm.nih.gov/pubmed/20403153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-100
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