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Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement.

The photocycle, electrical charge translocation, and release and uptake of protons from the aqueous phase and release and uptake of protons from the aqueous phase were investigated for bacteriorhodopsin mutants with aspartic acid-96 replaced by asparagine or glutamic acid. At neutral pH the main eff...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Holz, M, Drachev, L A, Mogi, T, Otto, H, Kaulen, A D, Heyn, M P, Skulachev, V P, Khorana, H G
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286872/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2648392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.7.2167
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