AP-1/σ1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory

Synaptic vesicle recycling involves AP-2/clathrin-mediated endocytosis, but it is not known whether the endosomal pathway is also required. Mice deficient in the tissue-specific AP-1–σ1B complex have impaired synaptic vesicle recycling in hippocampal synapses. The ubiquitously expressed AP-1–σ1A com...

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Detalhes bibliográficos
Main Authors: Glyvuk, Nataliya, Tsytsyura, Yaroslav, Geumann, Constanze, D'Hooge, Rudi, Hüve, Jana, Kratzke, Manuel, Baltes, Jennifer, Böning, Daniel, Klingauf, Jürgen, Schu, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868567/
https://ncbi.nlm.nih.gov/pubmed/20203623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.15
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