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Opioid and Cocaine Combined effect on Cocaine-Induced Changes in HPA and HPG Axes Hormones In Men

Nalbuphine, a mixed mu-/kappa-opioid analgesic, may have potential as a new medication for the treatment of cocaine abuse. Kappa-opioid agonists functionally antagonize some abuse-related and locomotor effects of cocaine, and both kappa-selective and mixed mu-/kappa-opioids reduce cocaine self-admin...

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Detalhes bibliográficos
Main Authors: Goletiani, Nathalie V., Mendelson, Jack H., Sholar, Michelle B., Siegel, Arthur J., Mello, Nancy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868518/
https://ncbi.nlm.nih.gov/pubmed/18848957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.09.007
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