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Function of MYO7A in the Human RPE and the Validity of Shaker1 Mice as a Model for Usher Syndrome 1B

PURPOSE. To investigate the function of MYO7A in human RPE cells and to test the validity of using shaker1 RPE in preclinical studies on therapies for Usher syndrome 1B by comparing human and mouse cells. METHODS. MYO7A was localized by immunofluorescence. Primary cultures of human and mouse RPE cel...

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Detalhes bibliográficos
Main Authors: Gibbs, Daniel, Diemer, Tanja, Khanobdee, Kornnika, Hu, Jane, Bok, Dean, Williams, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868451/
https://ncbi.nlm.nih.gov/pubmed/19643958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4032
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