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A Novel Haplotype with the R345W Mutation in the EFEMP1 Gene Associated with Autosomal Dominant Drusen in a Japanese Family

PURPOSE. To describe ophthalmic and molecular genetic findings in a family of Japanese patients with Malattia leventinese (ML)/Doyne honeycomb retinal dystrophy (DHRD), also known as autosomal dominant drusen. METHODS. Four patients with ML/DHRD, including a 42-year-old female proband, were ascertai...

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Detalhes bibliográficos
Main Authors: Takeuchi, Tomokazu, Hayashi, Takaaki, Bedell, Matthew, Zhang, Kang, Yamada, Hisashi, Tsuneoka, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868431/
https://ncbi.nlm.nih.gov/pubmed/19850834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4497
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