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Adenovirus Vectors Targeting Distinct Cell Types in the Retina

PURPOSE. Gene therapy for a number of retinal diseases necessitates efficient transduction of photoreceptor cells. Whereas adenovirus (Ad) serotype 5 (Ad5) does not transduce photoreceptors efficiently, previous studies have demonstrated improved photoreceptor transduction by Ad5 pseudotyped with Ad...

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Detalhes bibliográficos
Main Authors: Sweigard, J. Harry, Cashman, Siobhan M., Kumar-Singh, Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868406/
https://ncbi.nlm.nih.gov/pubmed/19892875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4367
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