CNS Leptin Action Modulates Immune Response and Survival in Sepsis

Sepsis describes a complex clinical syndrome that results from an infection, setting off a cascade of systemic inflammatory responses that can lead to multiple organ failure and death. Leptin is a 16 kDa adipokine that, among its multiple known effects, is involved in regulating immune function. Her...

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Autori principali: Tschöp, Johannes, Nogueiras, Ruben, Haas-Lockie, Sarah, Kasten, Kevin R., Castañeda, Tamara R., Huber, Nadine, Guanciale, Kelsey, Perez-Tilve, Diego, Habegger, Kirk, Ottaway, Nickki, Woods, Stephen C., Oldfield, Brian, Clarke, Iain, Chua, Streamson, Farooqi, I. Sadaf, O'Rahilly, Stephen, Caldwell, Charles C., Tschöp, Matthias H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868384/
https://ncbi.nlm.nih.gov/pubmed/20427662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4875-09.2010
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