Human immunodeficiency virus-infected T cells and monocytes are killed by monoclonal human anti-gp41 antibodies coupled to ricin A chain.

Two human monoclonal antibodies specific for the envelope glycoprotein (gp), gp41, of the human immunodeficiency virus were conjugated to deglycosylated ricin A chain. These immunotoxins killed human immunodeficiency virus-infected H9 (T cell) and U937 (monocyte) cell lines but were nontoxic to the...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Till, M A, Zolla-Pazner, S, Gorny, M K, Patton, J S, Uhr, J W, Vitetta, E S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2538826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1987
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