Synthesis, Solution, and Structural Characterization of Tetrahydrofuranyl-2,2-Bisphosphonic Acid Disodium Salt

Bisphosphonates are biologically relevant therapeutics for bone disorders and cancer. Reaction of γ-chlorobutyric acid, phosphorus acid, and phosphorus trichloride without the use of solvent gave the tetrahydrofuranyl-2,2-bisphosphonate sodium salt (Na(2)H(2)L). The Na(2)H(2)L was isolated, characte...

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Detalhes bibliográficos
Main Authors: Maltezou, Elena, Stylianou, Marios, Roy, Sudeshna, Drouza, Chryssoula, Keramidas, Anastasios D.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868181/
https://ncbi.nlm.nih.gov/pubmed/20467558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/563875
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