Cardiac phenotype and angiotensin II levels in AT(1a), AT(1b), and AT(2) receptor single, double, and triple knockouts

AIMS: Our aim was to determine the contribution of the three angiotensin (Ang) II receptor subtypes (AT(1a), AT(1b), AT(2)) to coronary responsiveness, cardiac histopathology, and tissue Ang II levels using mice deficient for one, two, or all three Ang II receptors. METHODS AND RESULTS: Hearts of kn...

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Main Authors: van Esch, Joep H.M., Gembardt, Florian, Sterner-Kock, Anja, Heringer-Walther, Silvia, Le, Thu H., Laßner, Dirk, Stijnen, Theo, Coffman, Thomas M., Schultheiss, Heinz-Peter, Danser, A.H. Jan, Walther, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868177/
https://ncbi.nlm.nih.gov/pubmed/20071356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq004
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