Antiretroviral Treatment Start-Time during Primary SIV(mac) Infection in Macaques Exerts a Different Impact on Early Viral Replication and Dissemination

BACKGROUND: The time of infection is rarely known in human cases; thus, the effects of delaying the initiation of antiretroviral therapy (ART) on the peripheral viral load and the establishment of viral reservoirs are poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: Six groups of macaques, infecte...

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Main Authors: Sellier, Pierre, Mannioui, Abdelkrim, Bourry, Olivier, Dereuddre-Bosquet, Nathalie, Delache, Benoit, Brochard, Patricia, Calvo, Julien, Prévot, Sophie, Roques, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868019/
https://ncbi.nlm.nih.gov/pubmed/20485497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010570
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