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The value of position-specific priors in motif discovery using MEME

BACKGROUND: Position-specific priors have been shown to be a flexible and elegant way to extend the power of Gibbs sampler-based motif discovery algorithms. Information of many types–including sequence conservation, nucleosome positioning, and negative examples–can be converted into a prior over the...

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Detalhes bibliográficos
Main Authors: Bailey, Timothy L, Bodén, Mikael, Whitington, Tom, Machanick, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868008/
https://ncbi.nlm.nih.gov/pubmed/20380693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-179
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