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The value of position-specific priors in motif discovery using MEME

BACKGROUND: Position-specific priors have been shown to be a flexible and elegant way to extend the power of Gibbs sampler-based motif discovery algorithms. Information of many types–including sequence conservation, nucleosome positioning, and negative examples–can be converted into a prior over the...

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Hlavní autoři: Bailey, Timothy L, Bodén, Mikael, Whitington, Tom, Machanick, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868008/
https://ncbi.nlm.nih.gov/pubmed/20380693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-179
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