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Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data

BACKGROUND: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-binding transcription factors control the transcription of a set of genes by detecting enrichment of known binding motifs...

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Détails bibliographiques
Auteurs principaux: McLeay, Robert C, Bailey, Timothy L
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868005/
https://ncbi.nlm.nih.gov/pubmed/20356413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-165
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