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Human hepatitis delta virus RNA subfragments contain an autocleavage activity.

Hepatitis delta virus (HDV) contains a single-stranded circular RNA genome of 1.7 kilobases. In this report we demonstrate that subfragments of HDV RNA can undergo autocatalytic cleavage. This cleavage requires at least 500 microM of Mg2+ or Ca2+, is not affected by varying the pH from 5.0 to 9.1, a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wu, H N, Lin, Y J, Lin, F P, Makino, S, Chang, M F, Lai, M M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286798/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2648383/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1831
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