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Contrasts between adaptive coding and noncoding changes during human evolution

Changes in non–protein-coding regulatory DNA sequences have been proposed to play distinctive roles in adaptive evolution. We analyzed correlations between gene functions and evidence for positive selection in a common statistical framework across several large surveys of coding and noncoding sequen...

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Auteurs principaux: Haygood, Ralph, Babbitt, Courtney C., Fedrigo, Olivier, Wray, Gregory A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867918/
https://ncbi.nlm.nih.gov/pubmed/20385805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911249107
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