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Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis

IL-33 is a novel member of the IL-1 family and ligand for the IL-1 receptor-related protein, ST2. Recent evidence suggests that the IL-33/ST2 axis plays a critical role in several autoimmune and inflammatory disorders; however, its role in inflammatory bowel disease (IBD) has not been clearly define...

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Bibliografski detalji
Glavni autori: Pastorelli, Luca, Garg, Rekha R., Hoang, Sharon B., Spina, Luisa, Mattioli, Benedetta, Scarpa, Melania, Fiocchi, Claudio, Vecchi, Maurizio, Pizarro, Theresa T.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867895/
https://ncbi.nlm.nih.gov/pubmed/20385815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912678107
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