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A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells

Tissue cells sense and respond to the stiffness of the surface on which they adhere. Precisely how cells sense surface stiffness remains an open question, though various biochemical pathways are critical for a proper stiffness response. Here, based on a simple mechanochemical model of biological fri...

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Autors principals: Walcott, Sam, Sun, Sean X.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867880/
https://ncbi.nlm.nih.gov/pubmed/20385838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912739107
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