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Epinephrine induces changes in the subcellular distribution of the inhibitory GTP-binding protein Gi alpha-2 and a 38-kDa phosphorylated protein in the human platelet.

By using antibodies specific for alpha subunits of inhibitory GTP-binding proteins (Gi alpha polypeptides) to probe Western blots of whole platelet protein, we detected Gi alpha-2 as the predominant Gi alpha species present in platelets. The subcellular compartmentalization of distinct Gi alpha-2-im...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Crouch, M F, Winegar, D A, Lapetina, E G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2538814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1776
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