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Induced pluripotent stem cells derived from mouse models of lysosomal storage disorders

Most lysosomal storage diseases (LSDs) are life-threatening genetic diseases. The pathogenesis of these diseases is poorly understood. Induced pluripotent stem (iPS) cell technology offers new opportunities for both mechanistic studies and development of stem cell– based therapies. Here we report th...

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Detalhes bibliográficos
Main Authors: Meng, Xing-Li, Shen, Jin-Song, Kawagoe, Shiho, Ohashi, Toya, Brady, Roscoe O., Eto, Yoshikatsu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867869/
https://ncbi.nlm.nih.gov/pubmed/20385825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002758107
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