HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors with a dismal prognosis and no effective conservative therapeutic strategies. Although it is demonstrated that histone deacetylases (HDACs), especially the class I HDACs HDAC1, 2 and 3 are highly expressed in thi...

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Main Authors: Schüler, Susanne, Fritsche, Petra, Diersch, Sandra, Arlt, Alexander, Schmid, Roland M, Saur, Dieter, Schneider, Günter
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867820/
https://ncbi.nlm.nih.gov/pubmed/20398369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-80
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