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Nuclear phosphoinositide 3-kinase β controls double-strand break DNA repair

Class I phosphoinositide 3-kinases are enzymes that generate 3-poly-phosphoinositides at the cell membrane following transmembrane receptor stimulation. Expression of the phosphoinositide 3-kinase β (PI3Kβ) isoform, but not its activity, is essential for early embryonic development. Nonetheless, the...

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Bibliografske podrobnosti
Main Authors: Kumar, Amit, Fernandez-Capetillo, Oscar, Carrera, Ana C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867755/
https://ncbi.nlm.nih.gov/pubmed/20368419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914242107
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