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Actin filament remodeling by actin depolymerization factor/cofilin

We investigate, using molecular dynamics, how the severing protein, actin depolymerization factor (ADF)/cofilin, modulates the structure, conformational dynamics, and mechanical properties of actin filaments. The actin and cofilactin filament bending stiffness and corresponding persistence lengths o...

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Autori principali: Pfaendtner, Jim, De La Cruz, Enrique M., Voth, Gregory A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867716/
https://ncbi.nlm.nih.gov/pubmed/20368459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911675107
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