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Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering
Mesenchymal stem/stromal cells (MSC) are typically used to generate bone tissue by a process resembling intramembranous ossification, i.e., by direct osteoblastic differentiation. However, most bones develop by endochondral ossification, i.e., via remodeling of hypertrophic cartilaginous templates....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867676/ https://ncbi.nlm.nih.gov/pubmed/20406908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000302107 |
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